Entuthukweni ethokozisayo elungisa kabusha umkhakha wezokunakekelwa kwempilo, umuthi omusha wekhwalithi ephezulu owaziwa ngokuthi i-Raloxifene Hydrochloride usungenile emakethe, wethula inketho yokwelapha eshintsha umdlalo ezimweni zezempilo ezahlukahlukene futhi ithuthukisa kakhulu izinga lempilo.Le mithi emisha isithole ukuqashelwa ngokushesha ngenxa yamandla ayo amangalisayo ekusingatheni izinkinga eziningi zempilo.
Ngokuyinhloko enqunyelwe ukuvimbela nokwelashwa kwe-osteoporosis kwabesifazane be-postmenopausal, i-Raloxifene Hydrochloride ibonakale iphumelela kakhulu ekwehliseni ukulahleka kwamathambo kanye nokwenza ngcono ukuminyana kwamaminerali amathambo.I-osteoporosis, isimo esibonakala ngokuncipha kwamathambo, ibeka engcupheni enkulu yokuphuka, ikakhulukazi kwabesifazane asebekhulile.Ngokusungulwa kwe-Raloxifene Hydrochloride, iziguli manje zikwazi ukufinyelela kumlingani onamandla ekulweni nezinkinga ezihlobene namathambo, ekugcineni zinciphisa ingozi yokuphuka nokuthuthukisa impilo yonke yamathambo.
Kodwa-ke, umthelela we-Raloxifene Hydrochloride ufinyelela kude nokwelashwa kwe-osteoporosis.Ucwaningo lwakamuva lwembule amandla alo ekuvimbeleni umdlavuza webele ohlaselayo kwabesifazane abangemva kokuya esikhathini abane-osteoporosis, kanye nokunciphisa ingozi yokuba nomdlavuza webele we-estrogen receptor-positive.Lokhu kutholakala okudabukisayo kulethe ithemba elisha ezigulini nakubasebenzi bezempilo ngokufanayo, kugcizelela ukubaluleka kwemithi yekhwalithi ephezulu ekuguquleni isimo sokuvinjelwa nokwelashwa komdlavuza webele.
Ngaphezu kwalokho, indlela eyingqayizivele ye-Raloxifene Hydrochloride inikeza izinzuzo ezengeziwe ezigulini.Ngokungafani nemithi yokwelapha yokubuyisela ama-hormone endabuko, lo muthi awunayo imiphumela emibi evame ukuhlotshaniswa ne-estrogen, okuwenza ube ngenye indlela ephephile.Ngaphezu kwalokho, i-Raloxifene Hydrochloride ibonise isithembiso ekwelapheni ezinye izimo zezokwelapha ezifana ne-endometrial hyperplasia, isandulela somdlavuza we-endometrial, kanye nokunciphisa ingozi yezenzakalo zenhliziyo nemithambo yegazi kwabesifazane be-postmenopausal.
Ukukhiqizwa kwe-Raloxifene Hydrochloride kubambelela ezindleleni zokulawula ikhwalithi ngokucophelela, kuqinisekisa kokubili ukuphepha nokusebenza kwayo.Izinkampani ezenza imithi zitshala izimali ezinkulu ocwaningweni nasekuthuthukisweni, zisebenzisa ubuchwepheshe obuthuthukisiwe kanye nemithethonqubo yokuhlola eqinile ukuze kugcinwe izindinganiso eziphakeme kakhulu.Lokhu kuzibophezela okungantengantengi kwikhwalithi kubalulekile ekuhlinzekeni iziguli ngemithi enamandla nethembekile ezingayethemba, ekugcineni kuholele emiphumeleni yezempilo ethuthukisiwe.
Ngokwethulwa kwe-Raloxifene Hydrochloride endaweni yokunakekelwa kwezempilo, iziguli ezibhekene ne-osteoporosis, umdlavuza webele, nezinye izimo zempilo ezihlobene nazo zingabheka phambili ekusaseni eliqhakazile.Amandla ayo angenakuqhathaniswa, angenayo imiphumela emibi ye-estrogen, iphawula igxathu elibalulekile eliya phambili ekufuneni izindlela zokwelapha eziphumelelayo, eziphephile, nezisezingeni eliphezulu.Njengoba lo muthi ophumelelayo uqhubeka nokubumba kabusha izinqubo zokunakekelwa kwezempilo, ochwepheshe balindele umthelela oguquguqukayo ezimpilweni zabantu abaningi emhlabeni jikelele.
Umshwana wokuzihlangula: Lesi sihloko senzelwe izinjongo zokwaziswa kuphela futhi akufanele sithathwe njengeseluleko sezokwelapha.Abafundi kufanele baxhumane nochwepheshe bezempilo ngaphambi kokuqala noma yimiphi imithi emisha noma uhlobo lokwelapha.
Isikhathi sokuthumela: Jul-08-2023