I-Pharmaceutical Raw Materials I-Medical Diuretics Spironolactone CAS 52-01-7

Incazelo emfushane:

Igama:	I-Spironolactone
I-CAS:	52-01-7
Ubumsulwa:	99%+
I-MOQ:	1g-1kg
Impilo yeshelufu:	Iminyaka Emibili

Intengo ye-FOB: :US $0.1 - 1,000 / amagremu

Inani elincane le-oda::1-100 amagremu

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Incazelo

I-Spironolactone, eyaziwa nangokuthi i-spironolactone, iwuhlobo lwe-potassium preserving diuretic drug. Incintisana ne-aldosterone kumaseli e-cortical epithelial yama-distal tubules futhi iqoqe imigudu ye-aldosterone receptor kumaseli okuhlosiwe, ukuze ivimbele indima ye-aldosterone ekuthuthukiseni ukushintshaniswa kwe-sodium ne-potassium, ikhulise ukukhishwa kwe-sodium chloride futhi ibe nomphumela wokukhipha isisu, kuyilapho ama-ion e-potassium angagcinwa. Ngakho-ke, i-spironolactone iwuhlobo lomuthi we-potassium ogcina i-diuretic.

Umsebenzi

I-Spironolactonei-potassium retention diuretic ebuthakathaka, eyaziwa nangokuthi i-spironolactone ne-spironolactone. Impushana ecwebezelayo emhlophe noma emhlophe qwa, ebaba kancane, engenaphunga noma enuka kancane i-mercaptan. Incibilika ku-chloroform, ayincibiliki emanzini, incibilika ku-ethanol, futhi incibilika kalula ku-benzene noma i-ethyl acetate. Ukwakheka kwayo kwamakhemikhali kufana ne-aldosterone. Ingakwazi ukuncintisana ne-aldosterone yama-aldosterone receptors ku-cytoplasm yama-tubules e-distal convoluted kanye nama-ducts aqoqayo, kuthinte ukubophezela kwe-aldosterone nama-receptors, ngaleyo ndlela kuvimbele ukuhlanganiswa kwamaprotheni e-aldosterone, ngaleyo ndlela kuvimbele ukushintshaniswa kwe-k+-na+, ukunciphisa ukuphuma kwe-potassium, nokudlala indima ekhona, yokugcinwa kwe-potassium lapho kukhona uhlobo olubili. i-spironolactone emakethe, elinye lingamaphilisi e-spironolactone, elinye ukhilimu we-spironolactone. Ukwakheka kwayo kanye nesimiso sokwelashwa kucishe kufane, kodwa ifomu lesidakamizwa lihlukile. I-Spironolactone yasungulwa iminyaka engaphezu kwengu-40. Ikakhulukazi isetshenziswa ekuhlanganisweni nezinye izidakamizwa ukwelapha umfutho wegazi ophakeme kanye nezifo ze-edema. Kodwa ngenxa yokuthi inganciphisa i-androgen emzimbeni, iphinde isetshenziswe emithini yokwelapha ukulahlekelwa izinwele zabesilisa. Umphumela we-anti hormone we-spironolactone ubuthakathaka kune-finasteride, ngakho-ke ifaneleka kakhulu ezigulini zesifazane ezinokulahlekelwa izinwele.

Isicelo

I-Aldactone isusa uketshezi oluningi emzimbeni ekuhlulekeni kwenhliziyo, ukucisha kwesibindi, nesifo sezinso.

Ingasetshenziswa futhi ngokuhlanganiswa nezinye izidakamizwa ukwelapha umfutho wegazi ophakeme, kanye nokwelapha i-diuretic-induced low potassium (hypokalemia).

I-Aldactone nayo isetshenziselwa ukulwa nemiphumela yokukhiqizwa ngokweqile kwe-adrenal aldosterone (hyperaldosteronism). Ukukhiqizwa ngokweqile kwe-Aldosterone kungenzeka kusuka esimila ku-adrenal gland noma izindlala ezikhulisiwe ze-adrenal (hyperplasia of the adrenal glands).

Izinhlobonhlobo zezindlela zokuthumela ongakhetha kuzo

Izindlela zokukhokha ezahlukahlukene ongakhetha kuzo

Isithembiso Sethu Kuwe:

Wonke umkhiqizo esiwuthengisayo ungu-100% Oyiqiniso Nekhwalithi Ephezulu.

Ukwaneliseka kwakho Kuqinisekisiwe ngo-100% noma ubuyiselwe imali yakho.

Ukupakisha

· 1kg/aluminium foil bag, enezikhwama ezimbili zepulasitiki ngaphakathi.
· 25kg/fiber drum, nezikhwama ezimbili zepulasitiki ngaphakathi.
Usayizi: ID 42cm * H52cm, 0.08m3 / isigubhu;
Isisindo Esiphelele:25kgs Isisindo Esiphelele:28kgs.

Izinzuzo Zethu

1. Ungoti Kwezemithi: -Njengoba sinesipiliyoni seminyaka embonini yezemithi, ithimba lethu liletha ubuchwepheshe obuningi ekuthuthukisweni komkhiqizo, ekukhiqizeni nasekusabalaliseni.

2. Imikhiqizo Esezingeni Eliphezulu: -Sithobela izindinganiso eziqinile zokulawula ikhwalithi kanye Nemikhuba Emihle Yokukhiqiza ukuze siqinisekise ukuphepha nokusebenza ngempumelelo kwemikhiqizo yethu yemithi.

3. Ibanga Lemikhiqizo Ehlukahlukene: -Iphothifoliyo yethu yomkhiqizo ebanzi ihlanganisa Izithako Zemithi Ezisebenzayo (ama-API), amafomu omthamo aqediwe, ama-intermediate emithi, kanye nezifiso

izixazululo zemithi ukuhlangabezana nezinhlobonhlobo zezidingo.

4. Amakhono Okwenza ngokwezifiso: -Sinikeza izixazululo ezihambisanayo zokuthuthukiswa komkhiqizo wemithi kanye nokukhiqiza ukuhlangabezana nezidingo eziyingqayizivele zamakhasimende ethu.

5. Ukufinyelela Emhlabeni Wonke:- -Sinobukhona obuqinile bamazwe ngamazwe, okusivumela ukuthi sikhonze amakhasimende nozakwethu emhlabeni wonke. Imikhiqizo yethu isatshalaliswa ezifundeni ezihlukahlukene, iqinisekisa ukufinyeleleka nokwethembeka.

6. Ukuthobela Umthetho:- -Sigcina ukunamathela ngokuqinile ezimisweni zokulawula zamazwe ngamazwe nemihlahlandlela, siqinisekisa ukuthi imikhiqizo yethu ihlangabezana nazo zonke izidingo zokulawula ezidingekayo.

7. Ukwesekwa Kwamakhasimende Okuphendulayo: -Ithimba lethu elizinikele lokusekela amakhasimende liyatholakala ukuze likusize ngokushesha ngemibuzo, ama-oda, nosekelo lobuchwepheshe.

8. Amanani Ancintisanayo: -Silwela ukunikeza amanani ancintisanayo emikhiqizo yethu yezemithi yekhwalithi ephezulu, okuvumela izixazululo ezingabizi kakhulu kumakhasimende ethu.

9. Imikhuba Esimeme: -Sizibophezele emikhubeni ebhekele imvelo ezinqubweni zethu zokukhiqiza nokusebenza, okunomthelela ekusaseni elisimeme.

10. Ukuqamba Nokucwaninga:- Sitshala imali ocwaningweni nasekuthuthukisweni ukuze sihlale siphambili entuthukweni yezemithi futhi silethe imikhiqizo emisha kumakhasimende ethu.

11. Ubambiswano Lwesikhathi Eside:- Siyabazisa ubudlelwano besikhathi eside namakhasimende ethu kanye nozakwethu, sikhuthaza ukwethembana nokusebenzisana ukuze siphumelele ngokufanayo.

12. Ukuxhumana Okusobala:- Sikholelwa ekuxhumaneni okusobala nokuvulelekile, siqinisekisa ukuthi amakhasimende ethu anolwazi futhi ayazethemba ekusebenzelaneni kwawo nathi.

Q1: Ungaqinisekisa kanjani ikhwalithi yomkhiqizo ngaphambi kokufaka i-oda?

1. Ungathola amasampula emikhiqizo.

2. Ungaphinda usithumele imininingwane noma izidingo zakho, futhi sizokwenzela umkhiqizo ngendlela oyifisayo.

Q2: Ngingaxhumana nawe kanjani?

Xhumana nathi nge-imeyili noma ngoWhatsapp. Isikhathi esimaphakathi sokuphendula amahora angu-0-4 phakathi namahora okusebenza futhi singaphansi kwamahora angu-24 ngezikhathi ezingezona ezokusebenza.

Q3: Ulenza kanjani i-oda?

-Xhumana nathi nganoma iyiphi yalezi zindlela ezingenhla..

-Sishiyele umlayezo ngomkhiqizo owufunayo.

-Incazelo ye-oda Inani.

-Sicela usitshele ikheli lakho lokuthumela.

-Umphathi wezokuthengisa ukunika ikhotheshini.

-Ukulethwa kosuku olufanayo ngemuva kokukhokha.